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DRUG CLASS:
DNA intercalator
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DNA intercalator
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News alerts, weekly reports and conference planners
Related drugs:
‹
daunorubicin (20)
aclarubicin (1)
mitoxantrone liposomal (0)
vosaroxin (0)
amonafide (0)
SQ3370 (0)
lyso-thermosensitive liposomal doxorubicin (0)
echinomycin (0)
2X-111 (0)
daunorubicin (20)
aclarubicin (1)
mitoxantrone liposomal (0)
vosaroxin (0)
amonafide (0)
SQ3370 (0)
lyso-thermosensitive liposomal doxorubicin (0)
echinomycin (0)
2X-111 (0)
›
Associations
(21)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML (NCT03280030)
Phase 2
Novartis Pharmaceuticals
Novartis Pharmaceuticals
Completed
Phase 2
Novartis Pharmaceuticals
Completed
Last update posted :
02/11/2025
Initiation :
04/06/2018
Primary completion :
11/14/2022
Completion :
11/14/2022
FLT3 • PML
|
FLT3 mutation
|
cytarabine • midostaurin • daunorubicin
Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma (NCT05958719)
Phase 2
Institute of Hematology & Blood Diseases Hospital, China
Institute of Hematology & Blood Disease...
Recruiting
Phase 2
Institute of Hematology & Blood Diseases Hospit...
Recruiting
Last update posted :
12/30/2024
Initiation :
03/02/2023
Primary completion :
12/30/2026
Completion :
03/02/2027
IFNG • IL6 • TNFA • IL10 • IFNA1
|
azacitidine • prednisone • Epidaza (chidamide) • Duoenda (mitoxantrone liposomal)
Optimum Induction Therapy of Low-risk APL (NCT05832320)
Phase N/A
Peking University People's Hospital
Peking University People's Hospital
Recruiting
Phase N/A
Peking University People's Hospital
Recruiting
Last update posted :
05/10/2024
Initiation :
01/01/2023
Primary completion :
12/31/2024
Completion :
12/31/2024
RARA • PML
|
etoposide IV • daunorubicin
Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia (VITAL) (NCT02658487)
Phase 2
Vanderbilt-Ingram Cancer Center
Vanderbilt-Ingram Cancer Center
Active, not recruiting
Phase 2
Vanderbilt-Ingram Cancer Center
Active, not recruiting
Last update posted :
05/03/2024
Initiation :
03/01/2016
Primary completion :
04/01/2019
Completion :
09/01/2024
SRC
|
cytarabine • Qinprezo (vosaroxin) • Starasid (cytarabine ocfosfate)
Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML (DaunoDouble) (NCT02140242)
Phase 3
Technische Universität Dresden
Technische Universität Dresden
Completed
Phase 3
Technische Universität Dresden
Completed
Last update posted :
09/15/2023
Initiation :
04/16/2014
Primary completion :
04/25/2022
Completion :
04/25/2022
NPPB
|
daunorubicin
Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia (NCT01238211)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 2
National Cancer Institute (NCI)
Completed
Last update posted :
03/01/2023
Initiation :
12/14/2010
Primary completion :
07/01/2013
Completion :
03/15/2021
RUNX1 • RUNX1T1
|
RUNX1-RUNX1T1 fusion • CBFB-MYH11 fusion
|
dasatinib • cytarabine • daunorubicin • Starasid (cytarabine ocfosfate)
Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia (NCT02914977)
Phase 1
Tara Lin
Tara Lin
Completed
Phase 1
Tara Lin
Completed
Last update posted :
01/14/2022
Initiation :
11/01/2016
Primary completion :
04/03/2019
Completion :
07/15/2021
CTNNB1
|
daunorubicin
Cytarabine (Ara-C) in Children With Acute Promyelocytic Leukemia (APL) (NCT01191541)
Phase 4
Xiaofan Zhu
Xiaofan Zhu
Completed
Phase 4
Xiaofan Zhu
Completed
Last update posted :
08/10/2021
Initiation :
05/01/2010
Primary completion :
02/01/2017
Completion :
02/01/2017
RARA
|
cytarabine • daunorubicin • arsenic trioxide
Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia (NCT01627041)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
06/21/2021
Initiation :
09/16/2011
Primary completion :
02/11/2016
RARA • CBFB
|
cytarabine • azacitidine • decitabine • daunorubicin • Starasid (cytarabine ocfosfate)
Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia (NCT01041703)
Phase 3
Eastern Cooperative Oncology Group
Eastern Cooperative Oncology Group
Recruiting
Phase 3
Eastern Cooperative Oncology Group
Recruiting
Last update posted :
12/08/2017
Initiation :
01/01/2011
Primary completion :
02/01/2019
HLA-DRB1
|
cytarabine • decitabine • daunorubicin • clofarabine
Safety and Efficacy Clinical Study of SNS-595 in Patients With Platinum-Resistant Ovarian Cancer (NCT00408603)
Phase 2
Sunesis Pharmaceuticals
Sunesis Pharmaceuticals
Completed
Phase 2
Sunesis Pharmaceuticals
Completed
Last update posted :
07/27/2017
Initiation :
12/20/2006
Primary completion :
06/09/2010
Completion :
06/09/2010
MUC16
|
cisplatin • Qinprezo (vosaroxin)
Idarubicin Overcomes MDR1 Induced Chemoresistance With Higher Induction Remission Rate and Quality Than Daunorubicin in Acute Myeloid Leukemia Patients (NCT01889407)
Phase N/A
Nanfang Hospital of Southern Medical University
Nanfang Hospital of Southern Medical Un...
Unknown status
Phase N/A
Nanfang Hospital of Southern Medical University
Unknown status
Last update posted :
04/21/2015
Initiation :
08/01/2013
Primary completion :
07/01/2016
Completion :
07/01/2016
ABCB1 • WT1 • GAPDH
|
ABCB1 overexpression
|
cytarabine • daunorubicin • idarubicin hydrochloride
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