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DRUG:
dianhydrogalactitol (VAL-083)
i
Other names:
VAL-083, NSC-1323313, DAG, DAG for Injection, VAL083, VAL 083, NSC1323313, NSC 1323313
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Associations
(2)
News
Trials
Company:
Kintara Therap, Valent Tech, Zhongheng Group
Drug class:
Alkylating agent
Related drugs:
‹
cyclophosphamide (66)
trabectedin (24)
STAR-001 (16)
lomustine (15)
carmustine (14)
lurbinectedin (11)
melphalan (9)
chlorambucil (7)
melphalan flufenamide (7)
temozolomide gel (7)
procarbazine hydrochloride (4)
OBI-3424 (4)
D19466 (4)
mitomycin (3)
thiotepa (3)
bendamustine RTD (2)
LP-284 (2)
fotemustine (2)
busulfan (2)
ACHM-025 (1)
BYON4413 (1)
FGX15-147-based ADC (1)
treosulfan (1)
IMGS-101 (1)
bendamustine rapid infusion (0)
ranimustine (0)
carmustine implant (0)
TL-118 (0)
altretamine (0)
mechlorethamine (0)
satraplatin (0)
PR104 (0)
pegylated liposomal mitomycin-c prodrug (0)
QBS72S (0)
mechlorethamine gel (0)
EX-204 (0)
captisol-enabled melphalan (0)
cyclophosphamide intravenous (0)
D 19575 (0)
CB1954 (0)
cyclophosphamide (66)
trabectedin (24)
STAR-001 (16)
lomustine (15)
carmustine (14)
lurbinectedin (11)
melphalan (9)
chlorambucil (7)
melphalan flufenamide (7)
temozolomide gel (7)
procarbazine hydrochloride (4)
OBI-3424 (4)
D19466 (4)
mitomycin (3)
thiotepa (3)
bendamustine RTD (2)
LP-284 (2)
fotemustine (2)
busulfan (2)
ACHM-025 (1)
BYON4413 (1)
FGX15-147-based ADC (1)
treosulfan (1)
IMGS-101 (1)
bendamustine rapid infusion (0)
ranimustine (0)
carmustine implant (0)
TL-118 (0)
altretamine (0)
mechlorethamine (0)
satraplatin (0)
PR104 (0)
pegylated liposomal mitomycin-c prodrug (0)
QBS72S (0)
mechlorethamine gel (0)
EX-204 (0)
captisol-enabled melphalan (0)
cyclophosphamide intravenous (0)
D 19575 (0)
CB1954 (0)
›
Associations
(2)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting (NCT02717962)
Phase 2
Kintara Therapeutics, Inc.
Kintara Therapeutics, Inc.
Active, not recruiting
Phase 2
Kintara Therapeutics, Inc.
Active, not recruiting
Last update posted :
11/22/2023
Initiation :
01/20/2017
Primary completion :
12/30/2023
Completion :
03/30/2024
MGMT
|
Avastin (bevacizumab) • temozolomide • dianhydrogalactitol (VAL-083)
Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression (NCT03050736)
Phase 2
Kintara Therapeutics, Inc.
Kintara Therapeutics, Inc.
Active, not recruiting
Phase 2
Kintara Therapeutics, Inc.
Active, not recruiting
Last update posted :
11/21/2023
Initiation :
12/17/2017
Primary completion :
11/22/2021
Completion :
12/30/2023
MGMT
|
dianhydrogalactitol (VAL-083)
Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma (NCT01478178)
Phase 1/2
DelMar Pharmaceuticals, Inc.
DelMar Pharmaceuticals, Inc.
Completed
Phase 1/2
DelMar Pharmaceuticals, Inc.
Completed
Last update posted :
01/20/2017
Initiation :
10/01/2011
Primary completion :
12/01/2015
Completion :
10/01/2016
IDH1 • MGMT
|
IDH1 mutation
|
dianhydrogalactitol (VAL-083)
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