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    BIOMARKER:

    CLDN6 positive

    i
    Other names: CLDN6, Claudin 6, Claudin-6, Skullin
    Entrez ID:
    9074
    Related biomarkers:
    Expression
    Apply
    Safety and Preliminary Efficacy Trial of BNT142 in Patients with CLDN6-positive Solid Tumors (NCT05262530)
    Phase 1/2
    BioNTech SE
    Recruiting
    Last update posted :
    01/31/2025
    Initiation :
    03/28/2022
    Primary completion :
    10/01/2025
    Completion :
    04/01/2026
    CLDN6
    |
    CLDN6 positive
    |
    BNT142
    A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors (CARVac) (NCT04503278)
    Phase 1
    BioNTech Cell & Gene Therapies GmbH
    Recruiting
    Last update posted :
    05/31/2024
    Initiation :
    09/16/2020
    Primary completion :
    01/01/2027
    Completion :
    01/01/2040
    AFP • CLDN6
    |
    CLDN6 expression • CLDN6 positive
    |
    BNT211
    CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors (NCT05410717)
    Phase 1
    Second Affiliated Hospital of Guangzhou Medical...
    Recruiting
    Last update posted :
    01/09/2024
    Initiation :
    06/01/2022
    Primary completion :
    06/01/2024
    Completion :
    05/31/2034
    AXL • MSLN • CLDN6 • GPC3
    |
    CLDN6 expression • CLDN6 positive
    |
    CLDN6-CAR-NK cell therapy
    A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors (NCT05735366)
    Phase 1
    Chugai Pharmaceutical
    Recruiting
    Last update posted :
    11/09/2023
    Initiation :
    04/18/2023
    Primary completion :
    12/31/2028
    Completion :
    12/31/2028
    CLDN6
    |
    CLDN6 positive
    |
    Actemra IV (tocilizumab) • SAIL66