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    BIOMARKER:

    CLDN6 expression

    i
    Other names: CLDN6, Claudin 6, Claudin-6, Skullin
    Entrez ID:
    9074
    Related biomarkers:
    Expression
    Apply
    A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors (CARVac) (NCT04503278)
    Phase 1
    BioNTech Cell & Gene Therapies GmbH
    Recruiting
    Last update posted :
    05/31/2024
    Initiation :
    09/16/2020
    Primary completion :
    01/01/2027
    Completion :
    01/01/2040
    AFP • CLDN6
    |
    CLDN6 expression • CLDN6 positive
    |
    BNT211
    A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications (NCT05317078)
    Phase 1
    Amgen
    Active, not recruiting
    Last update posted :
    01/11/2024
    Initiation :
    02/28/2023
    Primary completion :
    08/10/2026
    Completion :
    02/23/2028
    CLDN6
    |
    CLDN6 expression
    |
    AMG 794
    CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors (NCT05410717)
    Phase 1
    Second Affiliated Hospital of Guangzhou Medical...
    Recruiting
    Last update posted :
    01/09/2024
    Initiation :
    06/01/2022
    Primary completion :
    06/01/2024
    Completion :
    05/31/2034
    AXL • MSLN • CLDN6 • GPC3
    |
    CLDN6 expression • CLDN6 positive
    |
    CLDN6-CAR-NK cell therapy