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    CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer (NCT05029999)
    Phase 1
    University of Texas Southwestern Medical Center
    Recruiting
    Last update posted :
    06/14/2024
    Initiation :
    04/20/2022
    Primary completion :
    04/20/2025
    Completion :
    04/20/2025
    PD-L1
    |
    PD-L1 negative
    |
    pegylated liposomal doxorubicin • CDX-1140 • Mobista (CDX-301)
    In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors (NCT04616248)
    Phase 1
    University of Southern California
    Recruiting
    Last update posted :
    12/06/2023
    Initiation :
    01/09/2023
    Primary completion :
    01/09/2025
    Completion :
    01/09/2026
    HER-2
    |
    PD-L1 expression
    |
    CDX-1140 • Hiltonol (poly-ICLC) • Mobista (CDX-301)
    Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) (Mel66) (NCT04364230)
    Phase 1/2
    Craig L Slingluff, Jr
    Active, not recruiting
    Last update posted :
    10/11/2023
    Initiation :
    09/28/2020
    Primary completion :
    09/01/2024
    Completion :
    05/01/2025
    BRAF • CD4 • FOXP3
    |
    CDX-1140 • Hiltonol (poly-ICLC)