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    BIOMARKER:

    CDH1 mutation

    i
    Other names: CDH1, CD324, UVO, uvomorulin, Cadherin 1, type 1, E-cadherin
    Entrez ID:
    999
    Related biomarkers:
    Expression
    CNA
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    Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers (NCT04535414)
    Phase 2
    National Cancer Institute (NCI)
    Recruiting
    Last update posted :
    06/05/2024
    Initiation :
    06/22/2023
    Primary completion :
    12/31/2026
    Completion :
    12/31/2027
    CDH1
    |
    CDH1 mutation
    Early Onset and Familial Gastric Cancer Registry (NCT00582257)
    Phase N/A
    Memorial Sloan Kettering Cancer Center
    Active, not recruiting
    Last update posted :
    01/05/2024
    Initiation :
    12/01/2005
    Primary completion :
    12/01/2024
    Completion :
    12/01/2024
    CDH1
    |
    CDH1 mutation
    Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours (ROLo) (NCT03620643)
    Phase 2
    Royal Marsden NHS Foundation Trust
    Active, not recruiting
    Last update posted :
    12/22/2023
    Initiation :
    05/09/2019
    Primary completion :
    07/01/2024
    Completion :
    07/01/2024
    HER-2 • ER • CDH1
    |
    HER-2 positive • ER positive • HER-2 negative • CDH1 mutation • ER positive + HER-2 negative
    |
    Xalkori (crizotinib) • fulvestrant
    CDH1 Germline Mutations in Lobular Breast Cancer (NCT04206891)
    Phase N/A
    European Institute of Oncology
    Active, not recruiting
    Last update posted :
    09/21/2023
    Initiation :
    12/01/2018
    Primary completion :
    12/31/2021
    Completion :
    12/30/2023
    CDH1
    |
    CDH1 mutation
    The Gastric Cancer Foundation: A Gastric Cancer Registry (NCT01514045)
    Phase N/A
    Stanford University
    Recruiting
    Last update posted :
    02/24/2023
    Initiation :
    04/01/2011
    Primary completion :
    05/01/2023
    Completion :
    12/01/2025
    CDH1
    |
    CDH1 mutation
    Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer (NCT02451553)
    Phase 1
    University of Washington
    Completed
    Last update posted :
    06/07/2022
    Initiation :
    11/05/2015
    Primary completion :
    04/16/2022
    Completion :
    04/16/2022
    EGFR • HER-2 • KRAS • BRAF • NRAS • CDH1 • RAF1 • RAS
    |
    EGFR mutation • BRAF mutation • NRAS mutation • HER-2 mutation • CDH1 expression • CDH1 mutation
    |
    Gilotrif (afatinib) • capecitabine
    Confocal Endoscopic Microscopy for Detection of Early Stage Gastric Cancer in Subjects With Hereditary Diffuse Gastric Cancer Syndrome (NCT03648879)
    Phase 2
    National Cancer Institute (NCI)
    Completed
    Last update posted :
    07/12/2021
    Initiation :
    02/11/2019
    Primary completion :
    04/20/2020
    Completion :
    05/05/2020
    BRCA2 • CDH1 • CDH2 • CTNNA1
    |
    PALB2 mutation • CDH1 mutation
    Cremona Population-Based Gastric Tumors Registry (NCT01662739)
    Phase N/A
    Medicina e Arte Onlus
    Unknown status
    Last update posted :
    03/06/2017
    Initiation :
    01/01/2010
    Primary completion :
    12/01/2018
    Completion :
    12/01/2018
    CDH1
    |
    CDH1 mutation