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    BIOMARKER:

    CD70 expression

    i
    Other names: CD70, CD27L, CD27LG, TNFSF7
    Entrez ID:
    970
    Related biomarkers:
    Expression
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    Phase I Study of IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma (IMPACT) (NCT05353530)
    Phase 1
    University of Florida
    Recruiting
    Last update posted :
    02/28/2024
    Initiation :
    07/25/2023
    Primary completion :
    12/01/2027
    Completion :
    12/01/2042
    MGMT • CD70
    |
    CD70 expression
    |
    8R-70CAR T
    A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors (NCT06010875)
    Phase 1
    Chongqing Precision Biotech Co., Ltd
    Recruiting
    Last update posted :
    11/08/2023
    Initiation :
    11/30/2023
    Primary completion :
    12/31/2025
    Completion :
    09/30/2026
    IL6 • CD70
    |
    CD70 expression
    |
    cyclophosphamide • CD70 CAR-T
    A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors (NCT05518253)
    Phase 1
    Weijia Fang, MD
    Recruiting
    Last update posted :
    08/21/2023
    Initiation :
    05/30/2022
    Primary completion :
    05/30/2024
    Completion :
    05/30/2025
    IL6 • CD70
    |
    CD70 expression
    |
    cyclophosphamide • CD70 CAR-T
    A Clinical Research About CD70-positive Advanced/Metastatic Solid Tumors Treated by CD70-targeted CAR-T (NCT05468190)
    Phase 1
    Chongqing Precision Biotech Co., Ltd
    Recruiting
    Last update posted :
    08/17/2023
    Initiation :
    07/17/2022
    Primary completion :
    07/17/2024
    Completion :
    07/17/2025
    IL6 • CD70
    |
    CD70 expression
    |
    cyclophosphamide • CD70 CAR-T
    A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors (NCT05420545)
    Phase 1
    Chongqing Precision Biotech Co., Ltd
    Recruiting
    Last update posted :
    08/17/2023
    Initiation :
    12/31/2021
    Primary completion :
    12/31/2023
    Completion :
    12/31/2024
    IL6 • CD70
    |
    CD70 expression
    |
    cyclophosphamide • CD70 CAR-T
    Clinical Study of CD70-targeted CAR-T Therapy for Advanced/Advanced Renal Cancer (NCT05420519)
    Phase 1
    Chongqing Precision Biotech Co., Ltd
    Recruiting
    Last update posted :
    08/17/2023
    Initiation :
    12/31/2021
    Primary completion :
    12/31/2023
    Completion :
    12/31/2024
    IL6 • CD70
    |
    CD70 expression
    |
    cyclophosphamide • CD70 CAR-T
    CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma (NCT05948033)
    Phase 1/2
    Chinese PLA General Hospital
    Recruiting
    Last update posted :
    07/17/2023
    Initiation :
    07/15/2023
    Primary completion :
    12/31/2025
    Completion :
    12/31/2026
    IL6 • TNFA • CD70 • IL2 • IL10
    |
    CD70 expression
    |
    cyclophosphamide • UCL70802
    CD70 Targeted CAR-T Cells in CD70 Positive Advanced/Metastatic Solid Tumors (NCT05947487)
    Phase 1/2
    Chinese PLA General Hospital
    Recruiting
    Last update posted :
    07/17/2023
    Initiation :
    07/15/2023
    Primary completion :
    12/31/2025
    Completion :
    12/31/2026
    IL6 • TNFA • CD70 • IL2 • IL10
    |
    CD70 expression
    |
    albumin-bound paclitaxel • cyclophosphamide • UCL70802