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DRUG:
Cavatak (gebasaxturev)
i
Other names:
CVA21, Coxsackievirus A21, V937
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Associations
News
Trials
Company:
Merck (MSD)
Drug class:
ICAM-1 antagonist, CD55 inhibitor
Related drugs:
‹
VBI-002 (1)
VP301 (0)
BI-505 (0)
VBI-002 (1)
VP301 (0)
BI-505 (0)
›
Associations
News
Trials
Phase
Status
Apply
Phase
Status
Apply
CAVATAK® and Ipilimumab in Uveal Melanoma Metastatic to the Liver (VLA-024 CLEVER) (NCT03408587)
Phase 1b
Viralytics
Viralytics
Completed
Phase 1b
Viralytics
Completed
Last update posted :
05/04/2023
Initiation :
01/29/2018
Primary completion :
05/22/2019
Completion :
05/22/2019
PD-L1
|
Yervoy (ipilimumab) • Cavatak (gebasaxturev)
Pembrolizumab + CVA21 in Advanced NSCLC (NCT02824965)
Phase 1/2
Olivia Newton-John Cancer Research Institute
Olivia Newton-John Cancer Research Inst...
Active, not recruiting
Phase 1/2
Olivia Newton-John Cancer Research Institute
Active, not recruiting
Last update posted :
07/07/2021
Initiation :
08/09/2017
Primary completion :
07/01/2021
Completion :
10/01/2021
EGFR • PD-L1 • ALK
|
PD-L1 expression • EGFR mutation • ALK rearrangement
|
Keytruda (pembrolizumab) • Cavatak (gebasaxturev)
A Safety Study of Two Intratumoural Doses of Coxsackievirus Type A21 in Melanoma Patients (PSX-X03) (NCT00438009)
Phase 1
Viralytics
Viralytics
Completed
Phase 1
Viralytics
Completed
Last update posted :
07/01/2019
Initiation :
05/16/2007
Primary completion :
08/28/2009
Completion :
08/28/2009
ICAM1
|
Cavatak (gebasaxturev)
Coxsackie Virus A21 Administered Intravenously (IV) for Solid Tumour Cancers (PSX-X04) (NCT00636558)
Phase 1
Viralytics
Viralytics
Completed
Phase 1
Viralytics
Completed
Last update posted :
07/01/2019
Initiation :
02/29/2008
Primary completion :
01/12/2012
Completion :
01/12/2012
ICAM1
|
Cavatak (gebasaxturev)
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