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DRUG:

carmustine

Company:
Generic mfg.
Drug class:
DNA synthesis inhibitor, Alkylating agent
Related drugs:
Phase 1
Sidney Kimmel Comprehensive Cancer Center at Jo...
Recruiting
Last update posted :
02/24/2025
Initiation :
08/31/2022
Primary completion :
01/01/2026
Completion :
01/01/2027
PD-L1 • MSI • CD8 • PD-1 • CD4 • ICOS
|
temozolomide • carmustine • Zynyz (retifanlimab-dlwr)
Phase 2
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
02/06/2025
Initiation :
08/17/2015
Primary completion :
12/31/2025
Completion :
12/31/2025
MSI • CD4
|
PD-L1 expression
|
Keytruda (pembrolizumab) • Opdivo (nivolumab) • Avastin (bevacizumab) • Herceptin (trastuzumab) • Lynparza (olaparib) • Mekinist (trametinib) • cisplatin • Xalkori (crizotinib) • Tagrisso (osimertinib) • Tecentriq (atezolizumab) • Gilotrif (afatinib) • Yervoy (ipilimumab) • Ibrance (palbociclib) • dasatinib • Tafinlar (dabrafenib) • carboplatin • Imfinzi (durvalumab) • Vitrakvi (larotrectinib) • Imbruvica (ibrutinib) • gemcitabine • paclitaxel • Rituxan (rituximab) • docetaxel • 5-fluorouracil • sunitinib • everolimus • Vectibix (panitumumab) • temozolomide • Koselugo (selumetinib) • Perjeta (pertuzumab) • cytarabine • Kadcyla (ado-trastuzumab emtansine) • bortezomib • doxorubicin hydrochloride • Talzenna (talazoparib) • capecitabine • Piqray (alpelisib) • Xtandi (enzalutamide) • azacitidine • Cabometyx (cabozantinib tablet) • Balversa (erdafitinib) • Gazyva (obinutuzumab) • Mektovi (binimetinib) • albumin-bound paclitaxel • cyclophosphamide • Imjudo (tremelimumab-actl) • Cyramza (ramucirumab) • pemetrexed • fulvestrant • oxaliplatin • adavosertib (AZD1775) • etoposide IV • irinotecan • Halaven (eribulin mesylate) • Xpovio (selinexor) • Conmana (icotinib) • Pemazyre (pemigatinib) • Truqap (capivasertib) • methotrexate • Zarnestra (tipifarnib) • Aliqopa (copanlisib) • fexagratinib (ABSK091) • Ninlaro (ixazomib) • pegylated liposomal doxorubicin • epirubicin • sapanisertib (CB-228) • ipatasertib (RG7440) • Caprelsa (vandetanib) • vincristine • vinorelbine tartrate • Cometriq (cabozantinib capsule) • Tabrecta (capmatinib) • spartalizumab (PDR001) • taselisib (GDC-0032) • daunorubicin • omipalisib (GSK2126458) • ulixertinib (BVD-523) • mitoxantrone • Erivedge (vismodegib) • carmustine • bendamustine • bicalutamide • leucovorin calcium • Mvasi (bevacizumab-awwb) • Vegzelma (bevacizumab-adcd) • Zepzelca (lurbinectedin) • mitomycin • Jingzhuda (entinostat) • Recentin (cediranib) • Trazimera (trastuzumab-qyyp) • melphalan • GSK2636771 • Zirabev (bevacizumab-bvzr) • defactinib (VS-6063) • goserelin acetate • Zynyz (retifanlimab-dlwr) • fludarabine IV • Ostarine (enobosarm) • avadomide (CC-122) • vistusertib (AZD2014) • Myocet (non-pegylated liposomal doxorubicin) • mesna • vinblastine • Xofigo (radium Ra-223 dichloride) • lorvotuzumab mertansine (IMGN901) • Ampligen (rintatolimod) • E6201 • Fujovee (abivertinib) • Provenge (sipuleucel-T) • TQB2440 (pertuzumab biosimilar) • relatlimab (BMS-986016) • ABP 206 (nivolumab biosimilar) • Airuituo (bevacizumab biosimilar) • BCD-178 (pertuzumab biosimilar) • Beianting (bevacizumab biosimilar) • Boyounuo (bevacizumab biosimilar) • CC-90002 • EG1206A (pertuzumab biosimilar) • GB222 (bevacizumab biosimilar) • Hanbeitai (bevacizumab biosimilar) • ImmuniCell (autologous γδ T lymphocytes) • Leukine (sargramostim) • Vasforda (bevacizumab biosimilar) • celecoxib oral • cyclophosphamide intravenous • dexamethasone injection • ieramilimab (LAG525) • levoleucovorin calcium • methotrexate IV • sapitinib (AZD8931)
Phase 2
Washington University School of Medicine
Recruiting
Last update posted :
01/22/2025
Initiation :
01/16/2025
Primary completion :
07/31/2027
Completion :
07/31/2029
CD34
|
carmustine • melphalan • thiotepa
Phase 2
University of Southampton
Active, not recruiting
Last update posted :
12/05/2024
Initiation :
06/27/2022
Primary completion :
05/30/2026
Completion :
12/31/2026
CD20
|
CD34 positive
|
Keytruda (pembrolizumab) • carboplatin • Rituxan (rituximab) • cytarabine • ifosfamide • etoposide IV • carmustine
Phase 2
Imagine Institute
Completed
Last update posted :
06/19/2024
Initiation :
02/07/2018
Primary completion :
11/21/2022
Completion :
05/15/2023
TNFRSF8
|
TNFRSF8 positive
|
Adcetris (brentuximab vedotin) • carmustine
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
06/07/2024
Initiation :
10/12/2016
Primary completion :
05/10/2025
Completion :
05/10/2025
MYC • BCL2 • BCL6 • TNFA • CARD11 • TNFAIP3 • CD79A • GSTT1
|
CD79A mutation + CD79B mutation
|
Imbruvica (ibrutinib) • cytarabine • cyclophosphamide • etoposide IV • carmustine • melphalan • Starasid (cytarabine ocfosfate) • cyclophosphamide intravenous
Phase 1
City of Hope Medical Center
Active, not recruiting
Last update posted :
03/19/2024
Initiation :
06/08/2020
Primary completion :
09/18/2020
Completion :
12/31/2024
ALK • CD34
|
cytarabine • etoposide IV • etoposide oral • carmustine • melphalan • Simulect (basiliximab)
Phase 1
City of Hope Medical Center
Active, not recruiting
Last update posted :
03/19/2024
Initiation :
11/09/2012
Primary completion :
07/24/2021
Completion :
12/31/2024
CD34
|
cytarabine • etoposide IV • carmustine • melphalan • Simulect (basiliximab)
Phase 1/2
VBI Vaccines Inc.
Recruiting
Last update posted :
03/15/2024
Initiation :
12/06/2017
Primary completion :
07/01/2025
Completion :
08/01/2025
MGMT
|
lomustine • carmustine • VBI-1901
Phase 2
The Lymphoma Academic Research Organisation
Active, not recruiting
Last update posted :
03/15/2024
Initiation :
10/01/2016
Primary completion :
03/01/2019
Completion :
03/01/2025
CD20 • CCND1 • CD5
|
Chr t(11;14) • CD20 expression • CCND1 expression
|
cisplatin • cytarabine • Gazyva (obinutuzumab) • etoposide IV • dexamethasone • carmustine • melphalan
Phase 2
Leland Metheny
Recruiting
Last update posted :
02/28/2024
Initiation :
01/20/2023
Primary completion :
06/01/2024
Completion :
12/01/2024
IDH1 • MGMT
|
IDH2 mutation • IDH wild-type • MGMT expression
|
temozolomide • carmustine • Neupogen (filgrastim)
Phase 1
City of Hope Medical Center
Active, not recruiting
Last update posted :
02/22/2024
Initiation :
05/10/2000
Primary completion :
12/30/2024
Completion :
12/30/2024
CD34
|
cyclophosphamide • etoposide IV • carmustine • cyclophosphamide intravenous
Phase 1
M.D. Anderson Cancer Center
Completed
Last update posted :
12/19/2023
Initiation :
06/20/2011
Primary completion :
04/23/2020
Completion :
04/23/2020
IL2
|
cytarabine • etoposide IV • carmustine • melphalan • Proleukin (aldesleukin) • Depocyte (liposomal cytarabine)
Phase N/A
Memorial Sloan Kettering Cancer Center
Recruiting
Last update posted :
12/11/2023
Initiation :
09/09/2022
Primary completion :
09/01/2024
Completion :
09/01/2024
CD34
|
cytarabine • carmustine • melphalan
Phase 2
Masonic Cancer Center, University of Minnesota
Recruiting
Last update posted :
11/02/2023
Initiation :
04/20/2017
Primary completion :
09/30/2025
Completion :
04/30/2026
ALK • CD4 • TCL1A
|
ALK positive
|
cytarabine • cyclophosphamide • etoposide IV • carmustine • melphalan • Depocyte (liposomal cytarabine) • Neupogen (filgrastim) • cyclophosphamide intravenous
Phase 1
University of Nebraska
Completed
Last update posted :
10/10/2023
Initiation :
03/04/1996
Primary completion :
11/01/2014
Completion :
12/10/2014
CD20
|
CD20 expression
|
cytarabine • etoposide IV • carmustine • melphalan
Phase 1/2
University of Nebraska
Completed
Last update posted :
10/09/2023
Initiation :
11/12/2009
Primary completion :
07/27/2017
Completion :
07/27/2018
ALK • CD34
|
ALK negative
|
Rituxan (rituximab) • lenalidomide • cytarabine • etoposide IV • carmustine • melphalan • Truxima (rituximab-abbs) • Riabni (rituximab-arrx) • GB241 (rituximab biosimilar) • Novex (rituximab biosimilar) • Starasid (cytarabine ocfosfate)
Phase 2
University of Nebraska
Completed
Last update posted :
10/06/2023
Initiation :
05/08/2002
Primary completion :
11/01/2005
Completion :
03/12/2015
CD20
|
CD20 positive
|
Rituxan (rituximab) • cytarabine • etoposide IV • carmustine • melphalan • Gliadel Wafer (carmustine implant) • captisol-enabled melphalan
Phase 1/2
University of Nebraska
Completed
Last update posted :
09/28/2023
Initiation :
04/14/2006
Primary completion :
11/01/2014
Completion :
11/01/2014
CD34
|
cytarabine • bortezomib • etoposide IV • carmustine • melphalan
Phase 1/2
University of Nebraska
Completed
Last update posted :
09/07/2023
Initiation :
05/12/1998
Primary completion :
01/01/2001
Completion :
09/18/2009
CD20
|
CD20 positive
|
Rituxan (rituximab) • cytarabine • carmustine
Phase 2
University of Nebraska
Completed
Last update posted :
09/01/2023
Initiation :
09/01/2000
Primary completion :
01/01/2002
Completion :
01/01/2011
CD20
|
CD20 positive
|
Rituxan (rituximab) • cytarabine • etoposide IV • carmustine • melphalan
Phase 2
University of Nebraska
Completed
Last update posted :
09/01/2023
Initiation :
04/01/2000
Primary completion :
09/01/2005
Completion :
12/16/2014
CD20 • CD34
|
cytarabine • etoposide IV • carmustine • melphalan • Bexxar (iodine I 131 tositumomab) • captisol-enabled melphalan
Phase 1/2
AIDS Malignancy Consortium
Active, not recruiting
Last update posted :
08/01/2023
Initiation :
06/23/2016
Primary completion :
05/13/2021
Completion :
06/30/2025
ALK • CD4
|
ALK positive
|
cytarabine • etoposide IV • carmustine • melphalan • Starasid (cytarabine ocfosfate)
Phase 3
The First Affiliated Hospital with Nanjing Medi...
Recruiting
Last update posted :
07/04/2023
Initiation :
06/01/2023
Primary completion :
02/01/2026
Completion :
02/01/2028
CD34
|
cytarabine • etoposide IV • Epidaza (chidamide) • carmustine • melphalan
Phase 2
Memorial Sloan Kettering Cancer Center
Active, not recruiting
Last update posted :
06/30/2023
Initiation :
07/16/2013
Primary completion :
07/01/2024
Completion :
07/01/2024
CD34
|
cytarabine • etoposide IV • carmustine • Istodax (romidepsin) • melphalan
Phase N/A
Affiliated Hospital of Guangdong Medical Univer...
Recruiting
Last update posted :
06/28/2023
Initiation :
07/05/2023
Primary completion :
09/10/2025
Completion :
04/10/2026
CD34 • CD4
|
cytarabine • etoposide IV • carmustine • melphalan
Phase 2
City of Hope Medical Center
Recruiting
Last update posted :
06/22/2023
Initiation :
11/02/2021
Primary completion :
10/02/2027
Completion :
10/02/2027
CD34
|
cytarabine • etoposide IV • carmustine • melphalan • Simulect (basiliximab) • Starasid (cytarabine ocfosfate)
Phase N/A
Ruijin Hospital
Not yet recruiting
Last update posted :
05/18/2023
Initiation :
06/01/2023
Primary completion :
11/30/2024
Completion :
11/30/2025
BCL2
|
BCL2 positive
|
Venclexta (venetoclax) • cytarabine • etoposide IV • carmustine • melphalan
Phase 1
General Oncology, Inc.
Recruiting
Last update posted :
04/25/2023
Initiation :
01/13/2021
Primary completion :
12/01/2025
Completion :
12/01/2025
HER-2 • BRCA1 • BRCA2
|
BRCA2 mutation • BRCA1 mutation • HER-2 negative • PALB2 mutation
|
carmustine • melphalan • Mustargen (mechlorethamine)
Phase 1
Fred Hutchinson Cancer Center
Withdrawn
Last update posted :
01/13/2023
Initiation :
04/01/2023
Primary completion :
10/01/2025
Completion :
10/01/2027
BCL2 • BCL6
|
cytarabine • etoposide IV • carmustine • melphalan • Zynlonta (loncastuximab tesirine-lpyl) • Starasid (cytarabine ocfosfate)
Phase 2
Memorial Sloan Kettering Cancer Center
Completed
Last update posted :
06/21/2022
Initiation :
07/01/2008
Primary completion :
03/12/2021
Completion :
03/12/2021
CD20
|
CD20 expression
|
carboplatin • Rituxan (rituximab) • cyclophosphamide • ifosfamide • etoposide IV • mitoxantrone • carmustine
Phase 2
The First Affiliated Hospital with Nanjing Medi...
Active, not recruiting
Last update posted :
01/03/2022
Initiation :
02/01/2018
Primary completion :
12/31/2021
Completion :
12/31/2021
ALK • CD34
|
ALK positive
|
cytarabine • cyclophosphamide • etoposide IV • Epidaza (chidamide) • carmustine
Phase 3
National Heart, Lung, and Blood Institute (NHLBI)
Completed
Last update posted :
11/01/2021
Initiation :
12/01/2005
Primary completion :
08/01/2013
Completion :
08/01/2013
CD20 • CD8 • IL2RA • PTPRC • NCAM1 • ISG20
|
Rituxan (rituximab) • cytarabine • etoposide IV • carmustine • melphalan • Bexxar (iodine I 131 tositumomab)
Phase 1/2
Ohio State University Comprehensive Cancer Center
Active, not recruiting
Last update posted :
10/06/2021
Initiation :
09/10/2018
Primary completion :
12/31/2022
Completion :
12/31/2022
BCL2 • CD34
|
Venclexta (venetoclax) • cytarabine • etoposide IV • carmustine • melphalan • Starasid (cytarabine ocfosfate)
Phase 2
Stanford University
Completed
Last update posted :
09/23/2021
Initiation :
08/01/2006
Primary completion :
08/01/2007
Completion :
04/01/2010
HLA-DRB1 • HLA-B
|
cyclophosphamide • etoposide IV • sirolimus • carmustine • busulfan • cyclophosphamide intravenous
Phase N/A
Roswell Park Cancer Institute
Completed
Last update posted :
04/22/2021
Initiation :
06/29/2006
Primary completion :
07/09/2018
Completion :
07/09/2018
CD4
|
carboplatin • cyclophosphamide • etoposide IV • carmustine • melphalan • thiotepa • busulfan • cyclophosphamide intravenous
Phase 1/2
Weill Medical College of Cornell University
Completed
Last update posted :
02/21/2021
Initiation :
06/04/2014
Primary completion :
12/16/2019
Completion :
06/15/2020
CD34
|
Rituxan (rituximab) • cytarabine • etoposide IV • Campath (alemtuzumab) • carmustine • bendamustine • melphalan
Phase 3
Southwest Oncology Group
Completed
Last update posted :
02/02/2021
Initiation :
07/01/1997
Primary completion :
06/01/2008
Completion :
10/31/2013
CD20
|
Rituxan (rituximab) • doxorubicin hydrochloride • cyclophosphamide • etoposide IV • vincristine • prednisone • carmustine • cyclophosphamide intravenous
Phase 2
M.D. Anderson Cancer Center
Completed
Last update posted :
02/02/2021
Initiation :
11/14/2007
Primary completion :
03/05/2020
Completion :
03/05/2020
CD20 • CD34
|
CD20 positive
|
Rituxan (rituximab) • cytarabine • etoposide IV • carmustine • melphalan • Zevalin (ibritumomab tiuxetan) • Depocyte (liposomal cytarabine)