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DRUG:
cabiralizumab (BMS-986227)
i
Other names:
BMS-986227, FPA008, ONO-4687, FPA-008
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Associations
(1)
News
Trials
Company:
Amgen, BMS, Ono Pharmaceutical
Drug class:
CSF-1R inhibitor
Related drugs:
‹
TPX-0022 (8)
surufatinib (7)
HX301 (2)
chiauranib (1)
OPN-7486 (1)
ABSK021 (1)
Q702 (0)
AMB-05X (0)
C019199 (0)
LY3022855 (0)
axatilimab-csfr (0)
NMS-088 (0)
vimseltinib (0)
3D185 (0)
SYHA1817 (0)
BLZ-945 (0)
SU 14813 (0)
SYHA1813 (0)
TPX-0022 (8)
surufatinib (7)
HX301 (2)
chiauranib (1)
OPN-7486 (1)
ABSK021 (1)
Q702 (0)
AMB-05X (0)
C019199 (0)
LY3022855 (0)
axatilimab-csfr (0)
NMS-088 (0)
vimseltinib (0)
3D185 (0)
SYHA1817 (0)
BLZ-945 (0)
SU 14813 (0)
SYHA1813 (0)
›
Associations
(1)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma (NCT03502330)
Phase 1
Yale University
Yale University
Completed
Phase 1
Yale University
Completed
Last update posted :
07/03/2024
Initiation :
06/09/2018
Primary completion :
01/05/2022
Completion :
05/15/2024
PD-L1 • BRAF • CD8 • IFNG • CD163 • IL10 • CD40LG
|
EGFR mutation • EGFR T790M • ALK rearrangement
|
Opdivo (nivolumab) • cabiralizumab (BMS-986227) • sotigalimab (PYX-107)
Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer (NCT04331067)
Phase 1/2
Washington University School of Medicine
Washington University School of Medicine
Active, not recruiting
Phase 1/2
Washington University School of Medicine
Active, not recruiting
Last update posted :
05/16/2024
Initiation :
11/19/2020
Primary completion :
03/20/2023
Completion :
05/31/2026
HER-2 • ER
|
HER-2 negative
|
Opdivo (nivolumab) • carboplatin • paclitaxel • cabiralizumab (BMS-986227)
Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma (NCT03927105)
Phase 2
University of Michigan Rogel Cancer Center
University of Michigan Rogel Cancer Center
Completed
Phase 2
University of Michigan Rogel Cancer Center
Completed
Last update posted :
03/18/2024
Initiation :
04/25/2019
Primary completion :
11/01/2019
Completion :
07/06/2023
TNFRSF8
|
TNFRSF8 positive
|
Opdivo (nivolumab) • cabiralizumab (BMS-986227)
Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer (C4-MOSART) (NCT03431948)
Phase 1
University of Chicago
University of Chicago
Completed
Phase 1
University of Chicago
Completed
Last update posted :
02/16/2023
Initiation :
03/15/2018
Primary completion :
02/29/2020
Completion :
04/11/2022
EGFR
|
Opdivo (nivolumab) • cabiralizumab (BMS-986227) • urelumab (BMS-663513)
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