[{"id":"f4760edc-575b-4a03-b52a-92d92e44dfde","acronym":"","url":"https://clinicaltrials.gov/study/NCT02371135","created_at":"2021-01-18T11:17:42.064Z","updated_at":"2025-02-25T16:51:29.235Z","phase":"","brief_title":"Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes","source_id_and_acronym":"NCT02371135","lead_sponsor":"Memorial Sloan Kettering Cancer Center","biomarkers":" STK11 • MLH1 • MSH6 • MSH2 • SMAD4 • APC • EPCAM • BMPR1A","pipe":" | ","alterations":" MSH2 mutation • MLH1 mutation • PMS2 mutation","tags":["STK11 • MLH1 • MSH6 • MSH2 • SMAD4 • APC • EPCAM • BMPR1A"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e MSH2 mutation • MLH1 mutation • PMS2 mutation"],"overall_status":"Active, not recruiting","enrollment":" Enrollment 77","initiation":"Initiation: 02/01/2015","start_date":" 02/01/2015","primary_txt":" Primary completion: 02/01/2026","primary_completion_date":" 02/01/2026","study_txt":" Completion: 02/01/2026","study_completion_date":" 02/01/2026","last_update_posted":"2025-02-04"},{"id":"e561282a-18ae-455e-bea2-17d7fe3c9439","acronym":"PANEL","url":"https://clinicaltrials.gov/study/NCT02664389","created_at":"2021-01-18T12:59:11.654Z","updated_at":"2024-07-02T16:36:43.730Z","phase":"","brief_title":"Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation","source_id_and_acronym":"NCT02664389 - PANEL","lead_sponsor":"University Hospital, Rouen","biomarkers":" TP53 • BRCA2 • PTEN • STK11 • MLH1 • MSH6 • MSH2 • SMAD4 • BMPR1A","pipe":"","alterations":" ","tags":["TP53 • BRCA2 • PTEN • STK11 • MLH1 • MSH6 • MSH2 • SMAD4 • BMPR1A"],"overall_status":"Completed","enrollment":" Enrollment 289","initiation":"Initiation: 02/01/2016","start_date":" 02/01/2016","primary_txt":" Primary completion: 03/15/2017","primary_completion_date":" 03/15/2017","study_txt":" Completion: 03/15/2017","study_completion_date":" 03/15/2017","last_update_posted":"2020-06-30"}]