[{"id":"c658257f-75f4-4d06-aee3-2acd2eb60e2b","acronym":"","url":"https://clinicaltrials.gov/study/NCT01485861","created_at":"2021-01-17T17:57:48.754Z","updated_at":"2024-07-02T16:35:37.064Z","phase":"Phase 1/2","brief_title":"Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy","source_id_and_acronym":"NCT01485861","lead_sponsor":"Genentech, Inc.","biomarkers":" PTEN","pipe":" | ","alterations":" PTEN loss","tags":["PTEN"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e PTEN loss"," \u003cb class=\"violet\"\u003e|\u003c/b\u003e docetaxel • abiraterone acetate • ipatasertib (RG7440) • prednisone • apitolisib (GDC-0980)"],"overall_status":"Completed","enrollment":" Enrollment 298","initiation":"Initiation: 01/11/2012","start_date":" 01/11/2012","primary_txt":" Primary completion: 09/01/2015","primary_completion_date":" 09/01/2015","study_txt":" Completion: 08/31/2022","study_completion_date":" 08/31/2022","last_update_posted":"2023-09-14"}]