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DRUG:
alvocidib (DSP-2033)
i
Other names:
DSP-2033, L868275, HL-275, HMR 1275, IND 46211, L 868275, MDL-107826A, NSC 649890, flHMR-1275
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Associations
(8)
News
Trials
Company:
Sumitomo Pharma
Drug class:
CDK4 inhibitor, CDK6 inhibitor, CDK9 inhibitor
Related drugs:
‹
GDC-4198 (2)
TQB3616 (2)
PF-07220060 (1)
PF-06873600 (1)
AM-5992 (0)
FN-1501 (0)
PF-07224826 (0)
SYH2043 (0)
TY-0540 (0)
NUV-422 (0)
KB-0742 (8)
CYC065 (6)
VIP152 (5)
ME-522 (3)
TG02 (2)
BTX-A51 (1)
CDDD11-8 (1)
PRT2527 (1)
SLS009 (1)
AZD4573 (1)
A-1592668 (0)
TP-1287 (0)
BAY 1143572 (0)
CYC202 (0)
GDC-4198 (2)
TQB3616 (2)
PF-07220060 (1)
PF-06873600 (1)
AM-5992 (0)
FN-1501 (0)
PF-07224826 (0)
SYH2043 (0)
TY-0540 (0)
NUV-422 (0)
KB-0742 (8)
CYC065 (6)
VIP152 (5)
ME-522 (3)
TG02 (2)
BTX-A51 (1)
CDDD11-8 (1)
PRT2527 (1)
SLS009 (1)
AZD4573 (1)
A-1592668 (0)
TP-1287 (0)
BAY 1143572 (0)
CYC202 (0)
›
Associations
(8)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML (NCT04493099)
Phase 1/2
M.D. Anderson Cancer Center
M.D. Anderson Cancer Center
Withdrawn
Phase 1/2
M.D. Anderson Cancer Center
Withdrawn
Last update posted :
11/11/2020
Initiation :
10/01/2020
Primary completion :
10/12/2020
Completion :
10/12/2020
BCL2
|
Venclexta (venetoclax) • azacitidine • decitabine • alvocidib (DSP-2033)
Flavopiridol in Treating Patients With Previously Untreated or Relapsed Mantle Cell Lymphoma (NCT00005074)
Phase 2
NCIC Clinical Trials Group
NCIC Clinical Trials Group
Completed
Phase 2
NCIC Clinical Trials Group
Completed
Last update posted :
04/09/2020
Initiation :
01/24/2000
Primary completion :
02/20/2002
Completion :
09/22/2008
CD20 • CD5
|
CD20 positive • CD5 positive
|
alvocidib (DSP-2033)
Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors (NCT00957905)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 2
National Cancer Institute (NCI)
Completed
Last update posted :
03/10/2017
Initiation :
06/01/2009
Primary completion :
08/01/2014
Completion :
08/01/2014
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • oxaliplatin • leucovorin calcium • alvocidib (DSP-2033) • fluorouracil topical
Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (NCT00634244)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 2
National Cancer Institute (NCI)
Completed
Last update posted :
07/07/2015
Initiation :
10/01/2008
Primary completion :
09/01/2014
Completion :
10/01/2014
BCL2
|
carboplatin • cytarabine • etoposide IV • sirolimus • mitoxantrone • topotecan • alvocidib (DSP-2033)
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