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DRUG:
agerafenib (RXDX-105)
i
Other names:
RXDX-105, CEP-32496, AC013773, RXDX 105, RXDX105, CEP32496, CEP 32496, AC 013773
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Associations
(5)
News
Trials
Company:
Daiichi Sankyo, Roche
Drug class:
BRAF inhibitor, RET inhibitor, CS-1 inhibitor
Related drugs:
‹
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
encorafenib (63)
VS-6766 (27)
FORE-8394 (20)
RAF265 (7)
ERAS-254 (7)
GDC 0879 (6)
RAF709 (3)
HI-511 (1)
SB-590885 (1)
BGB-3245 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BDTX-4933 (0)
BMS-908662 (0)
PF-07799933 (0)
RX208 (0)
NSC311152 (0)
lenvatinib (90)
selpercatinib (67)
pralsetinib (49)
TAS0953/HM06 (7)
AST-487 (5)
EP0031 (4)
FHND5071 (4)
BOS-172738 (3)
HG-6-63-01 (2)
SY-5007 (2)
TY-1091 (2)
XMD15-44 (2)
TPX-0046 (2)
HSL468 (1)
HSL476 (1)
HSN608 (1)
LDD-2633 (1)
PLD-102 (1)
APS03118 (0)
BTG-002814 (0)
HS-10365 (0)
HS269 (0)
JNJ-26483327 (0)
LOXO-260 (0)
PLD-101 (0)
SYHA1815 (0)
SKI-G-801 (0)
elotuzumab (8)
PVX-410 (0)
SLAMF7 FPBMC (0)
vemurafenib (212)
dabrafenib (211)
PLX4720 (65)
encorafenib (63)
VS-6766 (27)
FORE-8394 (20)
RAF265 (7)
ERAS-254 (7)
GDC 0879 (6)
RAF709 (3)
HI-511 (1)
SB-590885 (1)
BGB-3245 (1)
PF-07284890 (1)
ARQ 736 (0)
ASN003 (0)
BDTX-4933 (0)
BMS-908662 (0)
PF-07799933 (0)
RX208 (0)
NSC311152 (0)
lenvatinib (90)
selpercatinib (67)
pralsetinib (49)
TAS0953/HM06 (7)
AST-487 (5)
EP0031 (4)
FHND5071 (4)
BOS-172738 (3)
HG-6-63-01 (2)
SY-5007 (2)
TY-1091 (2)
XMD15-44 (2)
TPX-0046 (2)
HSL468 (1)
HSL476 (1)
HSN608 (1)
LDD-2633 (1)
PLD-102 (1)
APS03118 (0)
BTG-002814 (0)
HS-10365 (0)
HS269 (0)
JNJ-26483327 (0)
LOXO-260 (0)
PLD-101 (0)
SYHA1815 (0)
SKI-G-801 (0)
elotuzumab (8)
PVX-410 (0)
SLAMF7 FPBMC (0)
›
Associations
(5)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Continued Access to RXDX-105 (NCT03784378)
Phase 1
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
Completed
Phase 1
Memorial Sloan Kettering Cancer Center
Completed
Last update posted :
10/05/2020
Initiation :
12/14/2018
Primary completion :
09/30/2020
Completion :
09/30/2020
BRAF
|
agerafenib (RXDX-105)
Study of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid Tumors (NCT01877811)
Phase 1
Hoffmann-La Roche
Hoffmann-La Roche
Completed
Phase 1
Hoffmann-La Roche
Completed
Last update posted :
04/25/2019
Initiation :
06/01/2013
Primary completion :
12/01/2018
Completion :
02/01/2019
BRAF
|
BRAF V600E • BRAF V600
|
agerafenib (RXDX-105)
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