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BIOMARKER:
AFP elevation
i
Other names:
AFP, Alpha-fetoprotein, FETA, HPAFP
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to learn more about our Premium Content:
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Entrez ID:
174
Related biomarkers:
Expression
Others
‹
›
Associations
(9)
News
Trials
Phase
Status
Apply
Phase
Status
Apply
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT (NCT04684368)
Phase 2
Children's Oncology Group
Children's Oncology Group
Recruiting
Phase 2
Children's Oncology Group
Recruiting
Last update posted :
06/10/2024
Initiation :
07/13/2021
Primary completion :
12/21/2029
Completion :
12/21/2029
NF1
|
AFP elevation
|
carboplatin • cyclophosphamide • ifosfamide • etoposide IV • mesna • thiotepa • Neulasta (pegfilgrastim) • Fulphila (pegfilgrastim-jmdb) • Neupogen (filgrastim) • Udenyca (pegfilgrastim-cbqv) • Ziextenzo (pegfilgrastim-bmez) • cyclophosphamide intravenous
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer (NCT00980460)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Active, not recruiting
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
05/21/2024
Initiation :
09/14/2009
Primary completion :
06/30/2020
Completion :
03/05/2025
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine • fluorouracil topical • dexrazoxane
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery (NCT03533582)
Phase 2/3
Children's Oncology Group
Children's Oncology Group
Active, not recruiting
Phase 2/3
Children's Oncology Group
Active, not recruiting
Last update posted :
04/22/2024
Initiation :
05/24/2018
Primary completion :
06/30/2026
Completion :
06/30/2026
SMARCB1 • AFP
|
AFP elevation
|
cisplatin • carboplatin • gemcitabine • sorafenib • 5-fluorouracil • doxorubicin hydrochloride • oxaliplatin • etoposide IV • irinotecan • vincristine • daunorubicin • fluorouracil topical
Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer (SWENOTECA-ABC) (NCT02341989)
Phase 3
St. Olavs Hospital
St. Olavs Hospital
Recruiting
Phase 3
St. Olavs Hospital
Recruiting
Last update posted :
07/06/2023
Initiation :
04/08/2015
Primary completion :
12/01/2035
Completion :
12/01/2035
AFP
|
AFP elevation
|
cisplatin • carboplatin • etoposide IV • bleomycin
A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma (NCT02423343)
Phase 1b/2
Eli Lilly and Company
Eli Lilly and Company
Completed
Phase 1b/2
Eli Lilly and Company
Completed
Last update posted :
09/09/2021
Initiation :
01/01/2015
Primary completion :
12/13/2018
Completion :
07/08/2020
EGFR • ALK • AFP
|
EGFR mutation • ALK positive • ALK fusion • AFP elevation
|
Opdivo (nivolumab) • cisplatin • galunisertib (LY2157299)
Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors (NCT01049230)
Phase 2
Massachusetts General Hospital
Massachusetts General Hospital
Active, not recruiting
Phase 2
Massachusetts General Hospital
Active, not recruiting
Last update posted :
01/05/2021
Initiation :
06/01/2010
Primary completion :
08/01/2022
Completion :
08/01/2022
AFP
|
AFP elevation
Sorafenib and Vorinostat in Treating Patients With Advanced Liver Cancer (NCT01075113)
Phase 1
Virginia Commonwealth University
Virginia Commonwealth University
Completed
Phase 1
Virginia Commonwealth University
Completed
Last update posted :
08/20/2019
Initiation :
08/10/2010
Primary completion :
02/02/2017
Completion :
07/18/2019
AFP
|
AFP elevation
|
sorafenib • Zolinza (vorinostat)
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer (NCT02265692)
Phase 3
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Recruiting
Phase 3
National Cancer Institute (NCI)
Recruiting
Last update posted :
12/22/2017
Initiation :
09/01/2009
Primary completion :
06/01/2016
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine
Radiolabeled Glass Beads (TheraSphere®) in Treating Patients With Primary Liver Cancer That Cannot Be Removed by Surgery (NCT00039078)
Phase 2
Allan Tsung
Allan Tsung
Withdrawn
Phase 2
Allan Tsung
Withdrawn
Last update posted :
06/26/2017
Initiation :
08/01/2000
Primary completion :
08/01/2000
Completion :
08/01/2000
AFP
|
AFP elevation
|
TheraSphere (yttrium 90 microspheres)
Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors (NCT00957905)
Phase 2
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 2
National Cancer Institute (NCI)
Completed
Last update posted :
03/10/2017
Initiation :
06/01/2009
Primary completion :
08/01/2014
Completion :
08/01/2014
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • oxaliplatin • leucovorin calcium • alvocidib (DSP-2033) • fluorouracil topical
Clemizole HCl for Subjects With Hepatocellular Carcinoma (NCT03069508)
Phase 2a
Eiger Group International, Inc.
Eiger Group International, Inc.
Unknown status
Phase 2a
Eiger Group International, Inc.
Unknown status
Last update posted :
03/03/2017
Initiation :
02/13/2017
Primary completion :
12/31/2017
Completion :
01/31/2018
AFP
|
AFP elevation
|
clemizole
Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment (NCT00453310)
Phase 2
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center
Completed
Phase 2
Memorial Sloan Kettering Cancer Center
Completed
Last update posted :
10/27/2015
Initiation :
03/01/2007
Primary completion :
11/01/2008
Completion :
11/01/2008
AFP
|
AFP elevation
|
cisplatin • sunitinib
Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery (NCT00608361)
Phase 1
National Cancer Institute (NCI)
National Cancer Institute (NCI)
Completed
Phase 1
National Cancer Institute (NCI)
Completed
Last update posted :
07/02/2015
Initiation :
10/01/2008
Primary completion :
08/01/2014
Completion :
08/01/2014
AFP
|
AFP elevation
|
dasatinib
Gemcitabine, Docetaxel, and Capecitabine in Treating Patients With Cancer of Unknown Primary Origin (NCT00119314)
Phase 2
University of Medicine and Dentistry of New Jersey
University of Medicine and Dentistry of...
Withdrawn
Phase 2
University of Medicine and Dentistry of New Jersey
Withdrawn
Last update posted :
05/27/2015
Initiation :
07/01/2004
Primary completion :
07/01/2005
Completion :
07/01/2005
AFP
|
AFP elevation
|
gemcitabine • docetaxel • capecitabine
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