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BIOMARKER:

AFP elevation

i
Other names: AFP, Alpha-fetoprotein, FETA, HPAFP
Entrez ID:
Related biomarkers:
Phase 2
Children's Oncology Group
Recruiting
Last update posted :
06/10/2024
Initiation :
07/13/2021
Primary completion :
12/21/2029
Completion :
12/21/2029
NF1
|
AFP elevation
|
carboplatin • cyclophosphamide • ifosfamide • etoposide IV • mesna • thiotepa • Neulasta (pegfilgrastim) • Fulphila (pegfilgrastim-jmdb) • Neupogen (filgrastim) • Udenyca (pegfilgrastim-cbqv) • Ziextenzo (pegfilgrastim-bmez) • cyclophosphamide intravenous
Phase 3
National Cancer Institute (NCI)
Active, not recruiting
Last update posted :
05/21/2024
Initiation :
09/14/2009
Primary completion :
06/30/2020
Completion :
03/05/2025
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine • fluorouracil topical • dexrazoxane
Phase 2/3
Children's Oncology Group
Active, not recruiting
Last update posted :
04/22/2024
Initiation :
05/24/2018
Primary completion :
06/30/2026
Completion :
06/30/2026
SMARCB1 • AFP
|
AFP elevation
|
cisplatin • carboplatin • gemcitabine • sorafenib • 5-fluorouracil • doxorubicin hydrochloride • oxaliplatin • etoposide IV • irinotecan • vincristine • daunorubicin • fluorouracil topical
Phase 3
St. Olavs Hospital
Recruiting
Last update posted :
07/06/2023
Initiation :
04/08/2015
Primary completion :
12/01/2035
Completion :
12/01/2035
AFP
|
AFP elevation
|
cisplatin • carboplatin • etoposide IV • bleomycin
Phase 1b/2
Eli Lilly and Company
Completed
Last update posted :
09/09/2021
Initiation :
01/01/2015
Primary completion :
12/13/2018
Completion :
07/08/2020
EGFR • ALK • AFP
|
EGFR mutation • ALK positive • ALK fusion • AFP elevation
|
Opdivo (nivolumab) • cisplatin • galunisertib (LY2157299)
Phase 2
Massachusetts General Hospital
Active, not recruiting
Last update posted :
01/05/2021
Initiation :
06/01/2010
Primary completion :
08/01/2022
Completion :
08/01/2022
AFP
|
AFP elevation
Phase 1
Virginia Commonwealth University
Completed
Last update posted :
08/20/2019
Initiation :
08/10/2010
Primary completion :
02/02/2017
Completion :
07/18/2019
AFP
|
AFP elevation
|
sorafenib • Zolinza (vorinostat)
Phase 3
National Cancer Institute (NCI)
Recruiting
Last update posted :
12/22/2017
Initiation :
09/01/2009
Primary completion :
06/01/2016
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine
Phase 2
Allan Tsung
Withdrawn
Last update posted :
06/26/2017
Initiation :
08/01/2000
Primary completion :
08/01/2000
Completion :
08/01/2000
AFP
|
AFP elevation
|
TheraSphere (yttrium 90 microspheres)
Phase 2
National Cancer Institute (NCI)
Completed
Last update posted :
03/10/2017
Initiation :
06/01/2009
Primary completion :
08/01/2014
Completion :
08/01/2014
AFP
|
AFP elevation
|
cisplatin • 5-fluorouracil • oxaliplatin • leucovorin calcium • alvocidib (DSP-2033) • fluorouracil topical
Phase 2a
Eiger Group International, Inc.
Unknown status
Last update posted :
03/03/2017
Initiation :
02/13/2017
Primary completion :
12/31/2017
Completion :
01/31/2018
AFP
|
AFP elevation
|
clemizole
Phase 2
Memorial Sloan Kettering Cancer Center
Completed
Last update posted :
10/27/2015
Initiation :
03/01/2007
Primary completion :
11/01/2008
Completion :
11/01/2008
AFP
|
AFP elevation
|
cisplatin • sunitinib
Phase 1
National Cancer Institute (NCI)
Completed
Last update posted :
07/02/2015
Initiation :
10/01/2008
Primary completion :
08/01/2014
Completion :
08/01/2014
AFP
|
AFP elevation
|
dasatinib
Phase 2
University of Medicine and Dentistry of New Jersey
Withdrawn
Last update posted :
05/27/2015
Initiation :
07/01/2004
Primary completion :
07/01/2005
Completion :
07/01/2005
AFP
|
AFP elevation
|
gemcitabine • docetaxel • capecitabine