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    BIOMARKER:

    AFP elevation

    i
    Other names: AFP, Alpha-fetoprotein, FETA, HPAFP
    Entrez ID:
    174
    Related biomarkers:
    Expression
    Others
    Apply
    A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT (NCT04684368)
    Phase 2
    Children's Oncology Group
    Recruiting
    Last update posted :
    06/10/2024
    Initiation :
    07/13/2021
    Primary completion :
    12/21/2029
    Completion :
    12/21/2029
    NF1
    |
    AFP elevation
    |
    carboplatin • cyclophosphamide • ifosfamide • etoposide IV • mesna • thiotepa • Neulasta (pegfilgrastim) • Fulphila (pegfilgrastim-jmdb) • Neupogen (filgrastim) • Udenyca (pegfilgrastim-cbqv) • Ziextenzo (pegfilgrastim-bmez) • cyclophosphamide intravenous
    Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer (NCT00980460)
    Phase 3
    National Cancer Institute (NCI)
    Active, not recruiting
    Last update posted :
    05/21/2024
    Initiation :
    09/14/2009
    Primary completion :
    06/30/2020
    Completion :
    03/05/2025
    AFP
    |
    AFP elevation
    |
    cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine • fluorouracil topical • dexrazoxane
    Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery (NCT03533582)
    Phase 2/3
    Children's Oncology Group
    Active, not recruiting
    Last update posted :
    04/22/2024
    Initiation :
    05/24/2018
    Primary completion :
    06/30/2026
    Completion :
    06/30/2026
    SMARCB1 • AFP
    |
    AFP elevation
    |
    cisplatin • carboplatin • gemcitabine • sorafenib • 5-fluorouracil • doxorubicin hydrochloride • oxaliplatin • etoposide IV • irinotecan • vincristine • daunorubicin • fluorouracil topical
    Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer (SWENOTECA-ABC) (NCT02341989)
    Phase 3
    St. Olavs Hospital
    Recruiting
    Last update posted :
    07/06/2023
    Initiation :
    04/08/2015
    Primary completion :
    12/01/2035
    Completion :
    12/01/2035
    AFP
    |
    AFP elevation
    |
    cisplatin • carboplatin • etoposide IV • bleomycin
    A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma (NCT02423343)
    Phase 1b/2
    Eli Lilly and Company
    Completed
    Last update posted :
    09/09/2021
    Initiation :
    01/01/2015
    Primary completion :
    12/13/2018
    Completion :
    07/08/2020
    EGFR • ALK • AFP
    |
    EGFR mutation • ALK positive • ALK fusion • AFP elevation
    |
    Opdivo (nivolumab) • cisplatin • galunisertib (LY2157299)
    Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors (NCT01049230)
    Phase 2
    Massachusetts General Hospital
    Active, not recruiting
    Last update posted :
    01/05/2021
    Initiation :
    06/01/2010
    Primary completion :
    08/01/2022
    Completion :
    08/01/2022
    AFP
    |
    AFP elevation
    Sorafenib and Vorinostat in Treating Patients With Advanced Liver Cancer (NCT01075113)
    Phase 1
    Virginia Commonwealth University
    Completed
    Last update posted :
    08/20/2019
    Initiation :
    08/10/2010
    Primary completion :
    02/02/2017
    Completion :
    07/18/2019
    AFP
    |
    AFP elevation
    |
    sorafenib • Zolinza (vorinostat)
    Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer (NCT02265692)
    Phase 3
    National Cancer Institute (NCI)
    Recruiting
    Last update posted :
    12/22/2017
    Initiation :
    09/01/2009
    Primary completion :
    06/01/2016
    AFP
    |
    AFP elevation
    |
    cisplatin • 5-fluorouracil • doxorubicin hydrochloride • irinotecan • Torisel (temsirolimus) • vincristine
    Radiolabeled Glass Beads (TheraSphere®) in Treating Patients With Primary Liver Cancer That Cannot Be Removed by Surgery (NCT00039078)
    Phase 2
    Allan Tsung
    Withdrawn
    Last update posted :
    06/26/2017
    Initiation :
    08/01/2000
    Primary completion :
    08/01/2000
    Completion :
    08/01/2000
    AFP
    |
    AFP elevation
    |
    TheraSphere (yttrium 90 microspheres)
    Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors (NCT00957905)
    Phase 2
    National Cancer Institute (NCI)
    Completed
    Last update posted :
    03/10/2017
    Initiation :
    06/01/2009
    Primary completion :
    08/01/2014
    Completion :
    08/01/2014
    AFP
    |
    AFP elevation
    |
    cisplatin • 5-fluorouracil • oxaliplatin • leucovorin calcium • alvocidib (DSP-2033) • fluorouracil topical
    Clemizole HCl for Subjects With Hepatocellular Carcinoma (NCT03069508)
    Phase 2a
    Eiger Group International, Inc.
    Unknown status
    Last update posted :
    03/03/2017
    Initiation :
    02/13/2017
    Primary completion :
    12/31/2017
    Completion :
    01/31/2018
    AFP
    |
    AFP elevation
    |
    clemizole
    Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment (NCT00453310)
    Phase 2
    Memorial Sloan Kettering Cancer Center
    Completed
    Last update posted :
    10/27/2015
    Initiation :
    03/01/2007
    Primary completion :
    11/01/2008
    Completion :
    11/01/2008
    AFP
    |
    AFP elevation
    |
    cisplatin • sunitinib
    Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery (NCT00608361)
    Phase 1
    National Cancer Institute (NCI)
    Completed
    Last update posted :
    07/02/2015
    Initiation :
    10/01/2008
    Primary completion :
    08/01/2014
    Completion :
    08/01/2014
    AFP
    |
    AFP elevation
    |
    dasatinib
    Gemcitabine, Docetaxel, and Capecitabine in Treating Patients With Cancer of Unknown Primary Origin (NCT00119314)
    Phase 2
    University of Medicine and Dentistry of New Jersey
    Withdrawn
    Last update posted :
    05/27/2015
    Initiation :
    07/01/2004
    Primary completion :
    07/01/2005
    Completion :
    07/01/2005
    AFP
    |
    AFP elevation
    |
    gemcitabine • docetaxel • capecitabine