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DRUG:
Ac-225 rosopatamab tetraxetan (CONV01-α)
i
Other names:
CONV01-α, CONV 01-α, CONV 01 alpha, Actinium-225 radiolabeled J591, alpha-emitter Actinium-225 conjugated to the anti-PSMA antibody J591, 225Ac-J591, Ac 225 MOAB J591, Actinium-J591
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News alerts, weekly reports and conference planners
Associations
News
Trials
Company:
Dominari Holdings, Weill Cornell Medical College
Drug class:
Alpha radiation emitter, PSMA inhibitor
Related drugs:
‹
Ac-225 ErbB3 targeted radiotherapy (4)
lintuzumab-Ac225 (4)
RYZ101 (2)
radium Ra-223 dichloride (2)
225Ac-FL-020 (1)
ORM-2110 (1)
BAY2701439 (1)
I-131-apamistamab (1)
Undisclosed EGFRvIII-targeted alpha therapy (1)
211At-OKT10-B10 (0)
212Pb-DOTAM-GRPR1 (0)
AAA817 (0)
AB001 (0)
FPI-1434 (0)
FPI-1966 (0)
FPI-2265 (0)
Iomab-ACT (0)
JNJ-6420 (0)
VMT-01 (0)
VMT-𝛼-NET (0)
[²¹¹At]PTT (0)
BAY 2315497 (0)
BAY 2287411 (0)
lutetium Lu 177 vipivotide tetraxetan (4)
PNT2002 (2)
INO-5401 (1)
JNJ-63898081 (1)
177Lu-LNC1003 (0)
177Lu-P17-087 (0)
177Lu-P17-088 (0)
177Lu-PSMA-R2 (0)
CYT 500 (0)
TLX591 (0)
AB-2100 (0)
ALF501 (0)
CB307 (0)
CBP-1018 (0)
CC-1 (0)
CCW702 (0)
HPN424 (0)
INO-5150 (0)
BIND-014 (0)
177 Lu-FC705 (0)
AMG 160 (0)
G-202 (0)
REGN5678 (0)
Ac-225 ErbB3 targeted radiotherapy (4)
lintuzumab-Ac225 (4)
RYZ101 (2)
radium Ra-223 dichloride (2)
225Ac-FL-020 (1)
ORM-2110 (1)
BAY2701439 (1)
I-131-apamistamab (1)
Undisclosed EGFRvIII-targeted alpha therapy (1)
211At-OKT10-B10 (0)
212Pb-DOTAM-GRPR1 (0)
AAA817 (0)
AB001 (0)
FPI-1434 (0)
FPI-1966 (0)
FPI-2265 (0)
Iomab-ACT (0)
JNJ-6420 (0)
VMT-01 (0)
VMT-𝛼-NET (0)
[²¹¹At]PTT (0)
BAY 2315497 (0)
BAY 2287411 (0)
lutetium Lu 177 vipivotide tetraxetan (4)
PNT2002 (2)
INO-5401 (1)
JNJ-63898081 (1)
177Lu-LNC1003 (0)
177Lu-P17-087 (0)
177Lu-P17-088 (0)
177Lu-PSMA-R2 (0)
CYT 500 (0)
TLX591 (0)
AB-2100 (0)
ALF501 (0)
CB307 (0)
CBP-1018 (0)
CC-1 (0)
CCW702 (0)
HPN424 (0)
INO-5150 (0)
BIND-014 (0)
177 Lu-FC705 (0)
AMG 160 (0)
G-202 (0)
REGN5678 (0)
›
Associations
News
Trials
Phase
Status
Apply
Phase
Status
Apply
Re-treatment 225Ac-J591 for mCRPC (NCT04576871)
Phase 1
Weill Medical College of Cornell University
Weill Medical College of Cornell Univer...
Recruiting
Phase 1
Weill Medical College of Cornell University
Recruiting
Last update posted :
10/31/2023
Initiation :
10/29/2020
Primary completion :
12/31/2025
Completion :
12/31/2026
CYP17A1
|
Ac-225 rosopatamab tetraxetan (CONV01-α)
Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC (NCT04506567)
Phase 1/2
Weill Medical College of Cornell University
Weill Medical College of Cornell Univer...
Recruiting
Phase 1/2
Weill Medical College of Cornell University
Recruiting
Last update posted :
08/28/2023
Initiation :
08/18/2020
Primary completion :
06/30/2025
Completion :
06/30/2027
CYP17A1
|
Ac-225 rosopatamab tetraxetan (CONV01-α)
ACTInium-J591 Radionuclide Therapy in PSMA-Detected Metastatic HOrmone-Sensitive Recurrent Prostate CaNcer (ACTION) (NCT05567770)
Phase 1
Weill Medical College of Cornell University
Weill Medical College of Cornell Univer...
Withdrawn
Phase 1
Weill Medical College of Cornell University
Withdrawn
Last update posted :
08/24/2023
Initiation :
12/01/2023
Primary completion :
01/01/2025
Completion :
01/01/2030
FOLH1
|
FOLH1 expression
|
Ac-225 rosopatamab tetraxetan (CONV01-α)
Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer (NCT04886986)
Phase 1/2
Weill Medical College of Cornell University
Weill Medical College of Cornell Univer...
Suspended
Phase 1/2
Weill Medical College of Cornell University
Suspended
Last update posted :
08/21/2023
Initiation :
06/30/2021
Primary completion :
12/24/2024
Completion :
12/27/2027
CYP17A1
|
lutetium zadavotide guraxetan (PNT2002) • Ac-225 rosopatamab tetraxetan (CONV01-α)
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