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BIOMARKER:

STMN2-H

i
Other names: STMN2, Stathmin 2, SCG10, SCGN10, Superior Cervical Ganglion-10 Protein, Stathmin-Like 2, Stathmin-2, Neuronal Growth-Associated Protein (Silencer Element), Superior Cervical Ganglia, Neural Specific 10, Neuron-Specific Growth-Associated Protein, Protein SCG10
Entrez ID:
2ms
Finally, analysis of The Cancer Genome Atlas patient data showed that high STMN2 levels correlate with complete regression of tumors in response to taxane treatment. Collectively, this study reveals a recurring mechanism of PRMT5i resistance in LUAD and identifies collateral sensitivities that have potential clinical relevance.
Preclinical • Journal
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KRAS (KRAS proto-oncogene GTPase) • TP53 (Tumor protein P53) • PRMT5 (Protein Arginine Methyltransferase 5) • STMN2 (Stathmin 2)
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STMN2-H
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paclitaxel