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BIOMARKER:

PTEN mutation

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Other names: PTEN, Phosphatase and tensin homolog, Mutated In Multiple Advanced Cancers 1, Phosphatase And Tensin Homolog, Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase And Dual-Specificity Protein Phosphatase PTEN, MMAC1, TEP1, MMAC1 Phosphatase And Tensin Homolog Deleted On Chromosome 10, Mitochondrial Phosphatase And Tensin Protein Alpha, Phosphatase And Tensin-Like Protein, Protein Tyrosine Phosphatase, Mitochondrial PTENalpha, PTENbeta, PTEN1, CWS1, GLM2, MHAM




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Include preclinical:
Prostate Cancer
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RG7440
bicalutamide
panitumumab
talazoparib
CB-228
capivasertib
atezolizumab + RG7440
LY3023414
pembrolizumab + GSK2636771
enzalutamide capsule + CC-115
ARQ 751
MK-2206
TAS-117
GDC-0032
nivolumab + ipilimumab
abiraterone acetate + RG7440
alpelisib
atezolizumab
vemurafenib
osimertinib
everolimus + SNX-631
MLN4924
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AZD6482
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A66
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GSK2636771 + A66
TGX-221
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AMG 479
RTB101 + RAF265
cetuximab
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Immunotherapy