^
    BIOMARKER:

    PTEN deletion

    i
    Other names: PTEN, Phosphatase and tensin homolog, Mutated In Multiple Advanced Cancers 1, Phosphatase And Tensin Homolog, Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase And Dual-Specificity Protein Phosphatase PTEN, MMAC1, TEP1, MMAC1 Phosphatase And Tensin Homolog Deleted On Chromosome 10, Mitochondrial Phosphatase And Tensin Protein Alpha, Phosphatase And Tensin-Like Protein, Protein Tyrosine Phosphatase, Mitochondrial PTENalpha, PTENbeta, PTEN1, CWS1, GLM2, MHAM




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    Include preclinical:
    Prostate Cancer
    Melanoma
    HER2 Positive Breast Cancer
    Gastric Cancer
    Colorectal Cancer
    Breast Cancer
    Endometrial Cancer
    Solid Tumor
    Ovarian Cancer
    Triple Negative Breast Cancer
    Lung Adenocarcinoma
    Chordoma
    Glioma
    Glioblastoma
    Non Small Cell Lung Cancer
    Renal Cell Carcinoma
    everolimus
    RG7440
    bevacizumab + temsirolimus
    GSK2636771
    olaparib
    AZD8186
    avelumab
    vemurafenib
    bevacizumab + nanoparticle albumin-bound rapamycin
    darolutamide
    apalutamide
    enzalutamide capsule + CC-115
    pembrolizumab + GSK2636771
    dabrafenib
    atezolizumab + RG7440
    trastuzumab
    enzalutamide capsule
    enzalutamide capsule + capivasertib
    MK-2206
    CI-1040
    CB-228
    MEN1611
    alpelisib
    lapatinib
    panitumumab
    abiraterone acetate
    MLN4924
    capivasertib
    apalutamide + AZD4635
    AZD4635
    GDC-0941
    GSK2636771 + ENUM004
    AVTX-006
    PD-0325901 + PF-04691502
    PF-04691502
    selumetinib + MK-2206
    cetuximab
    erlotinib
    mTORC1 inhibitor
    Immunotherapy
    ATM kinase inhibitor
    PDGFR inhibitor
    PDGFR inhibitor + HDAC inhibitor