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BIOMARKER:

NOTCH1 mutation

i
Other names: NOTCH1, TAN1




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Include preclinical:
Chronic Lymphocytic Leukemia
Non Small Cell Lung Cancer
Diffuse Large B Cell Lymphoma
T Acute Lymphoblastic Leukemia
Adenoid Cystic Carcinoma
Prolymphocytic Leukemia
Mantle Cell Lymphoma
Triple Negative Breast Cancer
Squamous Cell Carcinoma of Head and Neck
Colorectal Cancer
zanubrutinib
venetoclax + ibrutinib
tislelizumab
tretinoin
rituximab
obinutuzumab + GS-9973
venetoclax
Compound E
nirogacestat
WNT974
CB-839
IACS-010759
ofatumumab
BMF-219
obinutuzumab
ibrutinib + rituximab + obinutuzumab
Immunotherapy
ibrutinib
sintilimab + fruquintinib