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BIOMARKER:
MSI-H/dMMR + TMB-H + PD-L1 negative
i
Other names:
MSI | Microsatellite instability, TMB | Tumor Mutational Burden, PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
Associations
(3)
News
Trials
C4 | Sensitive
D | Sensitive
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
CD Protein Inhibitors
Immune Checkpoint Inhibitors
Immunotherapy
Chemotherapy
DNA
BCL Inhibitors
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Pancreatic Cancer
Uterine Cancer
pembrolizumab
C4
MSI-H/dMMR + TMB-H + PD-L1 negative
|
Uterine Cancer
|
pembrolizumab
D
MSI-H/dMMR + TMB-H + PD-L1 negative
|
Pancreatic Cancer
|
pembrolizumab
gemcitabine + paclitaxel
C4
MSI-H/dMMR + TMB-H + PD-L1 negative
|
Pancreatic Cancer
|
gemcitabine + paclitaxel
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