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BIOMARKER:
MSI-H/dMMR + POLE mutation
i
Other names:
MSI-H, Microsatellite instability - high, dMMR, POLE1, DNA Polymerase Epsilon Catalytic Subunit, DNA Polymerase Epsilon Catalytic Subunit A, Polymerase (DNA) Epsilon Catalytic Subunit, DNA Polymerase II Subunit A, Polymerase (DNA Directed) Epsilon Catalytic Subunit, DNA Polymerase Epsilon Catalytic Subunit Protein, Polymerase (DNA Directed) Epsilon
Associations
(4)
News
Trials
C3 | Sensitive
C4 | Sensitive
C3 | Resistant
C4 | Resistant
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Drug categories
CD Protein Inhibitors
Immune Checkpoint Inhibitors
Immunotherapy
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Gastric Cancer
Colorectal Cancer
Solid Tumor
Non Small Cell Lung Cancer
dostarlimab-gxly
C3
MSI-H/dMMR + POLE mutation
|
Gastric Cancer
|
dostarlimab-gxly
C3
MSI-H/dMMR + POLE mutation
|
Colorectal Cancer
|
dostarlimab-gxly
C3
MSI-H/dMMR + POLE mutation
|
Solid Tumor
|
dostarlimab-gxly
pembrolizumab
C4
MSI-H/dMMR + POLE mutation
|
Non Small Cell Lung Cancer
|
pembrolizumab
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