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BIOMARKER:
MGMT unmethylation
i
Other names:
MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
Associations
(15)
News
Trials
B | Sensitive
C3 | Sensitive
B | Resistant
C3 | Resistant
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Drug categories
Chemotherapy
DNA
Immunotherapy
Interferons
CD Protein Inhibitors
Immune Checkpoint Inhibitors
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Epigenetics
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Serine-Threonine Kinase Inhibitors
Tyrosine Kinase Inhibitors
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Glioblastoma
Glioma
temozolomide + interferon α-2b
B
MGMT unmethylation
|
Glioma
|
temozolomide + interferon α-2b
temozolomide
B
MGMT unmethylation
|
Glioblastoma
|
temozolomide
cemiplimab-rwlc + INO-5401 + INO-9012
C3
MGMT unmethylation
|
Glioblastoma
|
cemiplimab-rwlc + INO-5401 + INO-9012
VAL-083
C3
MGMT unmethylation
|
Glioblastoma
|
VAL-083
NOX-A12
C3
MGMT unmethylation
|
Glioblastoma
|
NOX-A12
temozolomide + ABT-888
C3
MGMT unmethylation
|
Glioblastoma
|
temozolomide + ABT-888
abemaciclib
C3
MGMT unmethylation
|
Glioblastoma
|
abemaciclib
nivolumab + aglatimagene besadenovec
C3
MGMT unmethylation
|
Glioma
|
nivolumab + aglatimagene besadenovec
UCPVax
C3
MGMT unmethylation
|
Glioblastoma
|
UCPVax
anlotinib
C3
MGMT unmethylation
|
Glioma
|
anlotinib
BAL101553
C3
MGMT unmethylation
|
Glioblastoma
|
BAL101553
C3
MGMT unmethylation
|
Glioblastoma
|
sunitinib + temozolomide
C3
MGMT unmethylation
|
Glioblastoma
|
sunitinib + temozolomide
nivolumab + ipilimumab
C3
MGMT unmethylation
|
Glioblastoma
|
nivolumab + ipilimumab
pembrolizumab
C3
MGMT unmethylation
|
Glioblastoma
|
pembrolizumab
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