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    BIOMARKER:

    MCL1 overexpression

    i
    Other names: MCL1, MCL1 Apoptosis Regulator BCL2 Family Member, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, Myeloid Cell Leukemia Sequence 1 (BCL2-Related), MCL1 BCL2 Family Apoptosis Regulator, Bcl-2-Related Protein EAT/Mcl1, Myeloid Cell Leukemia 1, Bcl-2-Like Protein 3, Bcl2-L-3, Mcl1/EAT, BCL2L3, BCL2 Family Apoptosis Regulator, Myeloid Cell Leukemia ES, MCL1-ES, MCL1L, MCL1S, Mcl-1, EAT, TM




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    Include preclinical:
    Chronic Lymphocytic Leukemia
    Multiple Myeloma
    Acute Myelogenous Leukemia
    Colorectal Cancer
    Mantle Cell Lymphoma
    venetoclax
    venetoclax + ONO-7475
    venetoclax + INCB59872
    venetoclax + trametinib
    ME-344
    APG1244 + MCL1 inhibitor
    APG1244