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BIOMARKER:
IDH2 R172K
i
Other names:
IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
Associations
(8)
News
Trials
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Immunotherapy
BCL Inhibitors
Epigenetics
Tyrosine Kinase Inhibitors
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Acute Myelogenous Leukemia
Cholangiocarcinoma
selinexor
C3
IDH2 R172K
|
Acute Myelogenous Leukemia
|
selinexor
venetoclax + enasidenib
C3
IDH2 R172K
|
Acute Myelogenous Leukemia
|
venetoclax + enasidenib
TQB3455
C3
IDH2 R172K
|
Acute Myelogenous Leukemia
|
TQB3455
venetoclax
C4
IDH2 R172K
|
Acute Myelogenous Leukemia
|
venetoclax
ponatinib
D
IDH2 R172K
|
Cholangiocarcinoma
|
ponatinib
bosutinib
D
IDH2 R172K
|
Cholangiocarcinoma
|
bosutinib
AZD0530
D
IDH2 R172K
|
Cholangiocarcinoma
|
AZD0530
dasatinib
D
IDH2 R172K
|
Cholangiocarcinoma
|
dasatinib
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