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BIOMARKER:
IDH2 mutation + Chr del(1p) + Chr del(19q)
i
Other names:
IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
Associations
(9)
News
Trials
A2 | Sensitive
C3 | Sensitive
A2 | Resistant
C3 | Resistant
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Drug categories
Chemotherapy
DNA
Tyrosine Kinase Inhibitors
CD Protein Inhibitors
Immune Checkpoint Inhibitors
Immunotherapy
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Oligodendroglioma
Glioma
temozolomide
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
temozolomide
bevacizumab
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
bevacizumab
carmustine
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
carmustine
lomustine
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
lomustine
PCV
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
PCV
cisplatin
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
cisplatin
carboplatin
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
carboplatin
etoposide IV
A2
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Oligodendroglioma
|
etoposide IV
nivolumab
C3
IDH2 mutation + Chr del(1p) + Chr del(19q)
|
Glioma
|
nivolumab
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