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CANCER:

Giant Cell Tumor of Bone





Show legend
Group by Gene:
Include preclinical:

0
RANK ligand inhibitor
denosumab
1
EGFR inhibitor
erlotinib
2
mTOR inhibitor
everolimus
3
PD1 inhibitor
pembrolizumab
4
EZH2 inhibitor
tazemetostat
5
Topoisomerase II inhibitor, EGFR inhibitor
gefitinib + mitoxantrone
6
PDGFR inhibitor, Bcr-abl tyrosine kinase inhibitor, c-KIT inhibitor
imatinib
7
CSF-1R inhibitor, c-KIT inhibitor, FLT3 inhibitor, AKT inhibitor, FMS kinase inhibitor
pexidartinib
8
VEGFR-2 inhibitor, RAF kinase inhibitor, BRAF inhibitor, PDGFR β antagonist
sorafenib
9
Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
dasatinib
10
SCF signal transduction pathway inhibitor, c-KIT inhibitor
YD312
11
VEGFR inhibitor, PDGFR inhibitor, c-KIT inhibitor
sunitinib
12
HER2 inhibitor, EGFR inhibitor
lapatinib
13
HER2 inhibitor, HER4 inhibitor, EGFR inhibitor
afatinib
14
PDGFR inhibitor, HDAC inhibitor
PDGFR inhibitor + HDAC inhibitor
15
PDGFR inhibitor
PDGFR inhibitor
No biomarker
EGFR expression
PIK3CA amplification
PIK3CA M1043I
TMB-H
SMARCB1 negative
COL6A3-CSF1 fusion
MSI-H/dMMR
PTEN deletion
H3F3A mutation + ARID2 mutation
AXL underexpression
STK33 underexpression