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BIOMARKER:

EGFR mutation + ANKRD1 overexpression

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Other names: ANKRD1, Ankyrin Repeat Domain 1, CARP, Ankyrin Repeat Domain-Containing Protein 1, Ankyrin Repeat Domain 1 (Cardiac Muscle), Cytokine-Inducible Gene C-193 Protein, Cytokine-Inducible Nuclear Protein, Cardiac Ankyrin Repeat Protein, C-193, CVARP, MCARP, ALRP, Epididymis Secretory Sperm Binding Protein, Liver Ankyrin Repeat Domain 1, BA320F15.2, ANKRD1, HA1A2, C193, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Include preclinical:
Non Small Cell Lung Cancer
Lung Adenocarcinoma
afatinib
osimertinib
EGFR inhibitor