^
    CANCER:

    Chronic Myelomonocytic Leukemia





    Show legend
    Group by Gene:
    Include preclinical:

    0
    DNA methylation inhibitor
    azacitidine
    1
    DNMT inhibitor, Cytidine deaminase inhibitor
    decitabine / cedazuridine
    2
    Bcl2 inhibitor
    venetoclax
    3
    GM-CSF inhibitor
    lenzilumab
    4
    Topoisomerase II inhibitor, DNA synthesis inhibitor, DNA-directed DNAP inhibitor, DNA intercalator
    cytarabine + daunorubicin
    5
    MEK inhibitor
    trametinib
    selumetinib
    6
    Bcr-abl tyrosine kinase inhibitor, Src kinase inhibitor, c-KIT inhibitor, PDGFR β antagonist, EphA2 receptor antagonist
    dasatinib
    7
    Jumonji H3K27 demethylase inhibitor
    GSKJ4
    No biomarker
    TP53 mutation
    RUNX1 mutation
    NRAS mutation
    CBL mutation
    KRAS mutation
    IDH2 mutation
    IDH1 mutation
    NPM1 mutation
    TET2 mutation
    RANBP2-ALK fusion
    CBL C384Y
    KRAS G12D
    NRAS G12D
    KDM6B overexpression + TET2 deletion