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BIOMARKER:
BRAF K601E
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
Associations
(7)
News
Trials
C3 | Sensitive
C4 | Sensitive
D | Sensitive
C3 | Resistant
C4 | Resistant
D | Resistant
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Include preclinical:
Drug categories
Threonine-Tyrosine Kinase Inhibitors
Serine-Threonine Kinase Inhibitors
Tyrosine Kinase Inhibitors
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Melanoma
Non Small Cell Lung Cancer
trametinib + dabrafenib
D
BRAF K601E
|
Melanoma
|
trametinib + dabrafenib
C4
BRAF K601E
|
Non Small Cell Lung Cancer
|
trametinib + dabrafenib
trametinib
C3
BRAF K601E
|
Melanoma
|
trametinib
trametinib + sorafenib
D
BRAF K601E
|
Melanoma
|
trametinib + sorafenib
sorafenib
D
BRAF K601E
|
Melanoma
|
sorafenib
vemurafenib
C4
BRAF K601E
|
Melanoma
|
vemurafenib
U0126
D
BRAF K601E
|
Melanoma
|
U0126
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