^
CANCER:

Anaplastic Astrocytoma





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Group by Gene:
0
DNA synthesis inhibitor
temozolomide
1
BRAF inhibitor
dabrafenib
2
BRAF inhibitor, BRAF V600E inhibitor
vemurafenib
3
PD1 inhibitor
nivolumab
4
TrkB receptor inhibitor, TrkC kinase inhibitor, TrkA receptor inhibitor
larotrectinib
5
Chemotherapy
PCV
6
PD-L1 inhibitor, MEK1 inhibitor
atezolizumab + cobimetinib
7
Tubulin polymerization promoter, Tubulin polymerization inhibitor, DNA synthesis inhibitor
carboplatin + temozolomide + vincristine
No biomarker
IDH1 R132H
IDH1 mutation
MGMT promoter methylation
BRAF mutation
BRAF V600
IDH2 mutation
ABCB1 G412G
TMB-H
NACC2-NTRK2 fusion
NRAS mutation
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation