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Association details:
Biomarker:SOX17 methylation
Cancer:Gastric Cancer
Regimen: (capecitabine + docetaxel + oxaliplatin)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Title:

Association between SOX17, Wif-1 and RASSF1A promoter methylation status and response to chemotherapy in patients with metastatic gastric cancer

Published date:
09/01/2020
Excerpt:
In the present group, the promoter of SOX17 gene was methylated in 61 out of 105 patients (58.1%)...Regarding response to treatment, complete response (CR) was seen in 0 out of 105 patients (0.0%), partial response (PR) was seen in 30 out of 105 patients (28.6%), stable disease (SD) was seen in 29 out of 105 patients (27.6%) and progressive disease (PD) in 46 out of 105 patients (43.8%).
DOI:
10.1515/cclm-2020-0662