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BIOMARKER:

FLT3 N676D + Y842C

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Entrez ID:
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Trials
FLT3 N676D + Y842C
AML
sorafenib
Resistant: D – Preclinical
FLT3 N676D + Y842C
AML
quizartinib
Resistant: D – Preclinical
FLT3 N676D + Y842C
AML
sorafenib + ARO-002
Sensitive: D – Preclinical